Welcome to our Metabolomics Services, where we offer comprehensive solutions for analyzing the complex world of metabolites. As a leading provider of bioanalytical services, Protheragen-ING Lab is dedicated to helping researchers, clinicians, and pharmaceutical companies unlock the secrets of metabolic pathways and uncover insights that drive scientific progress.
Introduction to metabolomics
Metabolomics is the comprehensive analysis of small molecule metabolites within a biological system. By analyzing the metabolic profile of a sample, researchers can gain valuable insights into the underlying biochemical processes and physiological states of an organism or biological system.
Our Metabolomics services leverage advanced analytical techniques and bioinformatics to provide a comprehensive assessment of metabolic pathways and biomarkers. Whether you're conducting research in drug discovery, toxicology, nutrition, or systems biology, our team of experts can help you unlock the power of metabolomics to drive your projects forward.
Our metabolomics capabilities
Targeted Metabolomics
Our targeted metabolomics approach allows for the quantitative analysis of a pre-defined set of known metabolites. This is particularly useful for investigating specific pathways or biomarkers of interest, such as those related to energy metabolism, amino acid homeostasis, or oxidative stress.
Untargeted Metabolomics
In contrast, our untargeted metabolomics services enable the simultaneous detection and identification of hundreds to thousands of metabolites, providing a global snapshot of the metabolic state of a sample. This unbiased approach is ideal for discovering novel biomarkers and elucidating complex metabolic networks.
Sample Preparation and Analysis
We offer comprehensive sample preparation and analysis services, including:
- Sample extraction and derivatization.
- High-resolution mass spectrometry (LC-MS/MS, GC-MS).
- NMR spectroscopy.
- Bioinformatics and data analysis.
Our state-of-the-art analytical platforms, combined with our team's expertise in experimental design and data interpretation, ensure high-quality, reproducible results.
Fig. 1 Targeted versus untargeted metabolomics approaches.[1]
Our expertise
Our team of highly skilled scientists and technicians has extensive experience in the field of metabolomics. Our expertise spans a wide range of applications, including:
- Biomarker Discovery: Identify key metabolites that can serve as diagnostic or prognostic indicators for various diseases and conditions.
- Pathway Analysis: Unravel the complex networks of metabolic pathways and understand how they are influenced by genetic, environmental, and physiological factors.
- Pharmaceutical Development: Assess the pharmacokinetics and pharmacodynamics of drug candidates, as well as their potential metabolic interactions.
- Nutritional Profiling: Analyze the metabolic fingerprints of various foods, supplements, and dietary interventions to understand their impact on human health.
- Environmental Monitoring: Investigate the presence and distribution of environmental contaminants and their metabolic effects on living organisms.
Applications of metabolomics
Metabolomics has a wide range of applications across various fields, including:
- Drug discovery and development.
- Biomarker identification.
- Toxicology and safety assessment.
- Nutrition and dietary intervention studies.
- Personalized medicine and precision healthcare.
- Environmental and agricultural research.
Why choose our metabolomics services?
- Experienced team of scientists and technicians with deep expertise in metabolomics
- Access to advanced analytical instrumentation and bioinformatics tools
- Customized experimental design and data analysis tailored to your research needs
- Commitment to data quality, reproducibility, and confidentiality
- Flexible service offerings, from sample preparation to full-scale metabolomics studies
To learn more about our Metabolomics Services and how we can support your research, please don't hesitate to contact us.
Reference
- De San-Martin BS, et al. (2021). "Metabolomics as A Potential Tool for The Diagnosis of Growth Hormone Deficiency (GHD): A Review." Arch Endocrinol Metab. 64(6), 654-663.